Bodhi Health has developed a breakthrough patented Curcumin (1) designed for sublingual absorption (under the tongue). This innovative delivery system allows curcumin to enter the bloodstream within minutes, bypassing digestion and first-pass liver metabolism. This enables curcumin to enter the bloodstream quickly and travel to key target tissues to suppress inflammation (and accompanying pain) and provide antioxidant effects.

Effects in the Body Curcumin, a compound in turmeric, has shown powerful anti-inflammatory, neuroprotective, exercise recovery and other important health effects in many studies. Bodhi Health Sublingual Curcumin is approved by health Canada for the purpose of supporting joint health and suppressing joint inflammatory conditions (i.e., osteoarthritis, other arthritic conditions, joint, muscle, tendon injuries etc.)

Curcumin is also shown to cross the blood-brain-barrier, where it provides documented neuroprotective effects (brain protective effects). Some small studies show that it improves memory and recall ability in healthy older subjects (2, 3). Experimental studies suggest that curcumin exerts other important protective effects on brain cells, potentially blocking steps involved in several age-related neurodegenerative conditions (2).

The Challenge:

Curcumin has very low absorption when taken orally—only 1–2% enters the bloodstream. Only small amounts are active even at high doses (1200–3000 mg/day) (4). This limits its effectiveness for severe pain or inflammation, often leading patients to rely on other medications.

The Bodhi Health Breakthrough Solution

To overcome the problems of poor absorption (bioavailability) and high-dose administration (1200 mg per day), Bodhi Health has developed a breakthrough patented Curcumin that provides for fast sublingual absorption (under the tongue). This innovative delivery system allows curcumin to enter the bloodstream within minutes, bypassing digestion and first-pass liver metabolism. This is also made possible using our proprietary oral film strip technology, which in published human research is shown to significantly increase blood levels of active constituents within minutes following sublingual administration (1,5)

Key Advantages:

• Direct bloodstream absorption through the oral mucosa

• Bypasses gut and liver breakdown, preserving curcumin’s potency

• Fast-acting: elevated blood levels in minutes

• Higher bioavailability than traditional oral supplements

Clinical studies using the same sublingual technology show significantly higher blood concentrations at 1-, 10-, and 30-minute post-administration compared to standard oral delivery (5).

References:

1. Patented Curcumin Shown to Improve Bioavailability 46x higher than standard curcumin. 2017 US Patent Approval. https://omniactives.com/press-releases/ultrasol-curcumin-line-curcuwin-granted-patent-for-sports-performance-benefits/ (and https://patents.google.com/patent/WO2012156979A1/en)

2. Curcumin Crosses Blood-Brain-Barrier Exerting Neuroprotective Effects. Adv Exp Med Biol, 2007. NEUROPROTECTIVE EFFECTS OF CURCUMIN - PMC

3. Curcumin Improves Memory in Subjects 50-90 Years Old Compared to Placebo. Am J Geriatric Psychiatry, 2018. https://www.sciencedirect.com/science/article/pii/S1064748117305110

4. Typical Poor Bioavailability of Phenolic Compounds (including Curcumin) Scholarly Community Encyclopedia, 2020. https://encyclopedia.pub/entry/3533

5. Breakthrough Proprietary Oral Film Technology: (Frontiers of Pharmacology, 2019. https://pubmed.ncbi.nlm.nih.gov/31551785/),